GitHub - PySimpleGUI/PySimpleGUI: Launched in 2018 Actively developed and supported. Supports tkinter, Qt, WxPython, Remi (in browser). Create custom layout GUI's simply. Python 2.7 & 3 Support. 100+ Demo programs & Cookbook for rapid start. Extensive documentation. Examples using Machine Learning(GUI, OpenCV Integration, Chatterbot), Floating Desktop Widgets, Matplotlib + Pyplot integration, add GUI to command line scripts, PDF & Image Viewer. For both beginning and advanced programmers .